APC Mouse Anti-Human CD127 [68C65P27]

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APC Mouse Anti-Human CD127 [68C65P27] 流式抗体

Purified APC-conjugated Recombinant Mouse Monoclonal Antibody

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货号	规格	价格
F101215
	25T	¥988.00
	100T	¥2180.00

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Human peripheral blood lymphocytes were stained with APC Mouse Anti-Human CD127 [68C65P27].

Human peripheral blood lymphocytes were stained with APC Mouse Anti-Human CD127 [68C65P27], Blue histogram. Un-stained control is Pink histogram.

Product Name	APC Mouse Anti-Human CD127
Description	Purified APC-conjugated Recombinant Mouse Monoclonal Antibody
Application Applications Legend: WB=Western Blotting IHC-P=Immunohistochemistry (Paraffin) IHC-F=Immunohistochemistry (Frozen) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	FC
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Clone No.	68C65P27
Isotype	IgG
Label	PE
Immunogen	Recombinant protein of human CD127
Format	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Recommended Usage	5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.
Synonyms	CD 127, CD127, CD127 antigen, CDw127, IL 7R alpha, IL 7R, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, IL7R, IL7RA, IL7RA_HUMAN, IL7Ralpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor, Interleukin 7 receptor isoform H5 6, Interleukin-7 receptor subunit alpha.
Uniprot ID	P16871
Gene ID	3575
Storage	Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. Stable for 24 months from date of receipt.
Precautions	APC Mouse Anti-Human CD127 [68C65P27] is for research use only and not for use in diagnostic or therapeutic procedures.

Background	CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Background

CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Cellular Location	Secreted and Cell membrane.

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F101215 APC Mouse Anti-Human CD127 [68C65P27]

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