Purified PE-Cy7-conjugated Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| F100214 | ||
| 25T | ¥998.00 | |
| 100T | ¥2280.00 |
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![PE-Cy7 Mouse Anti-Human CD4 [42D94J37]](https://files.epizyme.cn:5005/uploads/products/202506/F100214-1.png)
![PE-Cy7 Mouse Anti-Human CD4 [42D94J37]](https://files.epizyme.cn:5005/uploads/products/202506/F100214-2.png)
| Product Name | PE-Cy7 Mouse Anti-Human CD4 |
|---|---|
| Description | Purified PE-Cy7-conjugated Recombinant Mouse Monoclonal Antibody |
Application
|
FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 42D94J37 |
| Isotype | IgG |
| Label | PE-Cy7 |
| Immunogen | Recombinant protein of human CD45 |
| Format | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA. |
| Recommended Usage | 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. |
|---|---|
| Synonyms | CD 4, CD4 (L3T4), CD4, CD4 antigen (p55), CD4 antigen, CD4 molecule, CD4 receptor, CD4+ Lymphocyte deficiency, included, CD4_HUMAN, CD4mut, L3T4, Leu3, Ly-4, Lymphocyte antigen CD4, MGC165891, OTTHUMP00000238897, p55, T cell antigen T4, T cell antigen T4/LEU3, T cell differentiation antigen L3T4, T cell OKT4 deficiency, included, T cell surface antigen T4/Leu 3, T cell surface antigen T4/Leu3, T cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, W3/25, W3/25 antigen. |
| Uniprot ID | P01730 |
| Gene ID | 920 |
| Storage | Shipped on wet ice. Store undiluted between 2℃ and 8℃ and protected from prolonged exposure to light. Do not freeze. Stable for 24 months from date of receipt. |
| Precautions | PE-Cy7 Mouse Anti-Human CD4 [42D94J37] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
|---|
| Cellular Location | Cell membrane. Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum. |
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