Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| MR00002 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
| Product Name | Recombinant Anti-Fibronectin Mouse mAb [23L232H8] |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
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WB, ELISA, IF, IHC-P |
| Dilution | IHC-P 1:1,000; WB 1:1,000~1:5,000; IF 1:100~1:1,000; ELISA 1:10,000 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 23L232H8 |
| Isotype | IgG1 |
| Immunogen | Recombinant anti-Fibronectin monoclonal antibody recognizes endogenous levels of total Fibronectin protein. |
| Format | Purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. This antibody is purified through a protein G column. |
| Synonyms | CIG; Cold insoluble globulin; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; ED B; ED-B; fibronectin 1; FINC; FN 1; FN; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor; MSF; Transformation sensitive protein; FINC_HUMAN; Fibronectin; Cold-insoluble globulin; Ugl-Y3. |
|---|---|
| Calculated MW | 230~280 kDa |
| Primary Accession | P02751 |
| Gene ID | 2335 |
| Storage | Shipped at 4℃. Upon delivery aliquot. Store at 4℃ short term (1~2 weeks). Store at -20℃ for 2 years. Avoid freeze / thaw cycles. |
| Precautions | Anti-Fibronectin(1-4) Mouse mAb is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin (PubMed:3024962, PubMed:3900070, PubMed:3593230, PubMed:7989369). Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (PubMed:3024962, PubMed:3900070, PubMed:3593230, PubMed:7989369). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity). Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation (PubMed:34089617). |
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| Cellular Location | Secreted, extracellular space, extracellular matrix. |
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| Tissue Location | Expressed in the inner limiting membrane and around blood vessels in the retina (at protein level) (PubMed:29777959) Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine (PubMed:17614963). |
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