HRP(Horseradish Peroxidase)即辣根过氧化物酶，可以催化DAB、TMB等底物显色或催化ECL等化学发光试剂产生化学反应而发光。本产品为辣根过氧化物酶标记的经亲和纯化的山羊抗体，特异识别小鼠/兔IgG(H+L)，检测灵敏度高，本底低，对其它种属IgG无明显交叉反应，可用于Western Blot、ELISA和免疫组化检测。
免疫原 小鼠/兔IgG
缓冲液 10mM PBS(pH7.4)，50% glycerol
稳定剂 10mg/mL BSA(IgG-free and protease-free)
防腐剂 0.05% sodium thimerosal
推荐浓度 Inmunohisto/cytochemistry：1:200~1:1,000；
ELISA and Western Blot with chromogenic substrates：1:1,000~1:4,000；
Western Blot with ECL substrates：1:2,000~1:10,000。
1. 为了您的安全和健康，请穿实验服并戴一次性手套操作；
2. 本产品仅限科研使用。
Gu, T., Qi, Z., Wang, Y., Chen, S., Yan, J., Qiu, H., ... & Gong, J. (2023). An endophytic fungus interacts with the defensin-like protein OsCAL1 to regulate cadmium allocation in rice. Molecular Plant.(IF 27.5)
Huang, Y., Huang, J., Zhou, Q. X., Yang, C. X., Yang, C. P., Mei, W. Y., ... & Ding, Y. Q. (2021). ZFP804A mutant mice display sex-dependent schizophrenia-like behaviors. Molecular psychiatry, 26(6), 2514-2532.(IF 15.992)
Liu, Y., Zhai, E., Chen, J., Qian, Y., Zhao, R., Ma, Y., ... & Chen, J. (2022). m6A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels. Cancer Communications, 42(4), 327-344.(IF 15.283)
Huang, H., Li, N., Wei, X., Li, Q., Guo, J., Yang, G., ... & Wu, C. (2023). Biomimetic “Gemini nanoimmunoregulators” orchestrated for boosted photoimmunotherapy by spatiotemporally modulating PD-L1 and tumor-associated macrophages. Acta Pharmaceutica Sinica B.(IF 14.5)
Liang, J., Wei, J., Cao, J., Qian, J., Gao, R., Li, X., ... & Wang, X. (2023). In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation. Genome Biology, 24(1), 251.(IF 12.3)
Wang, N. N., Zhang, Y., Jiang, F., Zhu, D. L., Di, C. X., Hu, S. Y., ... & Guo, Y. (2023). Enhancer variants on chromosome 2p14 regulating SPRED2 and ACTR2 act as a signal amplifier to protect against rheumatoid arthritis. The American Journal of Human Genetics, 110(4), 625-637.(IF 11.043)
Li, M., Yang, G., Zheng, Y., Lv, J., Zhou, W., Zhang, H., ... & Liu, Y. (2023). NIR/pH-triggered aptamer-functionalized DNA origami nanovehicle for imaging-guided chemo-phototherapy. Journal of Nanobiotechnology, 21(1), 186.(IF 10.2)
Duan, Y. Y., Chen, X. F., Zhu, R. J., Jia, Y. Y., Huang, X. T., Zhang, M., ... & Yang, T. L. (2023). High-throughput functional dissection of noncoding SNPs with biased allelic enhancer activity for insulin resistance-relevant phenotypes. The American Journal of Human Genetics, 110(8), 1266-1288.(IF 9.8)
He, Z., Yu, C., Pan, Z., Li, X., Zhang, X., Huang, Q., ... & Liang, J. (2023). Erythrocyte membrane with CLIPPKF as biomimetic nanodecoy traps merozoites and attaches to infected red blood cells to prevent Plasmodium infection. Journal of Nanobiotechnology, 21(1), 1-17.(IF 9.429)
Gu, T. Y., Qi, Z. A., Chen, S. Y., Yan, J., Fang, Z. J., Wang, J. M., & Gong, J. M. (2023). Dual-function DEFENSIN 8 mediates phloem cadmium unloading and accumulation in rice grains. Plant Physiology, 191(1), 515-527.(IF 8.005)
Dai, M., Peng, W., Lin, L., Wu, Z. E., Zhang, T., Zhao, Q., ... & Li, F. (2023). Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii. Phytomedicine, 121, 155054.(IF 7.9)
Zhu, L., Chen, D., Zhu, Y., Pan, T., Xia, D., Cai, T., Lin, H., Lin, J., Jin, X., Wu, F., Yu, S., Zhu, K., Xu, L., & Chen, Y. (2021). GPX4-Regulated Ferroptosis Mediates S100-Induced Experimental Autoimmune Hepatitis Associated with the Nrf2/HO-1 Signaling Pathway. Oxidative medicine and cellular longevity, 2021, 6551069.(IF 7.31)
Zheng, H. L., Xu, W. N., Chen, P. B., Jiang, L. S., Zheng, X. F., & Jiang, S. D. (2022). Increased Expression of Prolyl Endopeptidase Induced by Oxidative Stress in Nucleus Pulposus Cells Aggravates Intervertebral Disc Degeneration. Oxidative Medicine and Cellular Longevity, 2022, 9731800-9731800.(IF 7.31)
Xu, H., Zeng, S., Wang, Y., Yang, T., Wang, M., Li, X., ... & Zhang, J. (2023). Cytoplasmic SIRT1 promotes paclitaxel resistance in ovarian carcinoma through increased formation and survival of polyploid giant cancer cells. The Journal of Pathology, 261(2), 210-226.(IF 7.3)
Wang, C. X., Wang, T. T., Zhang, K. D., Li, M. Y., Shen, Q. C., Lu, S. Y., & Zhang, J. (2022). Pan-KRAS inhibitors suppress proliferation through feedback regulation in pancreatic ductal adenocarcinoma. Acta Pharmacologica Sinica, 1-13.(IF 7.169)
Liu, Q., Zhao, S., Meng, F., Wang, H., Sun, L., Li, G., ... & Chen, F. (2021). Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma. Frontiers in Oncology, 11, 661157.(IF 6.244)
Yang, X., Chen, D., Zheng, S., Yi, M., Wang, S., Liu, Y., ... & Huang, Y. (2023). The Prmt5-Vasa module is essential for spermatogenesis in Bombyx mori. PLoS genetics, 19(1), e1010600.(IF 6.02)
Wang, S., Cheng, M., Peng, P., Lou, Y., Zhang, A., & Liu, P. (2021). Iron Released after Cryo-Thermal Therapy Induced M1 Macrophage Polarization, Promoting the Differentiation of CD4+ T Cells into CTLs. International journal of molecular sciences, 22(13), 7010.(IF 5.923)
Gao, M., Ma, Y., Luo, J., Li, D., Jiang, M., Jiang, Q., ... & Cui, L. (2021). The role of Nrf2 in the PM-induced vascular injury under real ambient particulate matter exposure in C57/B6 mice. Frontiers in pharmacology, 12, 618023.(IF 5.81)
Ding, H., Jiang, M., Li, D., Zhao, Y., Yu, D., Zhang, R., ... & Piao, J. (2021). Effects of Real-Ambient PM2. 5 Exposure on Lung Damage Modulated by Nrf2−/−. Frontiers in pharmacology, 12, 662664.(IF 5.81)
Jiang, H., Fang, Y., Wang, Y., Li, T., Lin, H., Lin, J., ... & Chen, Y. (2023). FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3. International Immunopharmacology, 116, 109762.(IF 5.714)
Zhang, Q., Chen, X., Hu, Y., Zhou, T., Du, M., Xu, R., ... & Li, J. (2023). BIRC5 Inhibition Is Associated with Pyroptotic Cell Death via Caspase3-GSDME Pathway in Lung Adenocarcinoma Cells. International Journal of Molecular Sciences, 24(19), 14663.(IF 5.6)
Chen, G., Zhang, H., Sun, H., Ding, X., Liu, G., Yang, F., ... & Yang, L. (2023). Bufalin targeting BFAR inhibits the occurrence and metastasis of gastric cancer through PI3K/AKT/mTOR signal pathway. Apoptosis, 1-16.(IF 5.561)
Xu, H. W., Fang, X. Y., Liu, X. W., Zhang, S. B., Yi, Y. Y., Chang, S. J., ... & Wang, S. J. (2023). α-Ketoglutaric acid ameliorates intervertebral disk degeneration by blocking the IL-6/JAK2/STAT3 pathway. American Journal of Physiology-Cell Physiology, 325(4), C1119-C1130.(IF 5.5)
Zhao, Y. C., Wang, C. C., Li, X. Y., Wang, D. D., Wang, Y. M., Xue, C. H., ... & Zhang, T. T. (2023). Supplementation of n-3 PUFAs in Adulthood Attenuated Susceptibility to Pentylenetetrazol Induced Epilepsy in Mice Fed with n-3 PUFAs Deficient Diet in Early Life. Marine Drugs, 21(6), 354.(IF 5.4)
Yang, Y., Wang, X., Chen, L., Wang, S., Han, J., Wang, Z., & Wen, M. (2023). A Compared Study of Eicosapentaenoic Acid and Docosahexaenoic Acid in Improving Seizure-Induced Cognitive Deficiency in a Pentylenetetrazol-Kindling Young Mice Model. Marine Drugs, 21(9), 464.(IF 5.4)
Hua, H., Pan, C., Chen, X., Jing, M., Xie, J., Gao, Y., ... & Li, P. (2023). Probiotic lactic acid bacteria alleviate pediatric IBD and remodel gut microbiota by modulating macrophage polarization and suppressing epithelial apoptosis. Frontiers in Microbiology, 14, 1168924.(IF 5.2)
Lai, T., Qiu, H., Si, L., Zhen, Y., Chu, D., & Guo, R. (2022). Long noncoding RNA BMPR1B-AS1 facilitates endometrial cancer cell proliferation and metastasis by sponging miR-7-2-3p to modulate the DCLK1/Akt/NF-κB pathway. Cell Cycle, 1-20.(IF 5.173)
Wang, Q., Wang, B., Ma, X., Zhuang, H., Xie, Z., Tang, C., ... & Chen, Y. (2023). Identification of a Novel Ferroptosis-Related Gene Signature for Predicting Prognosis and Responsiveness to Immunotherapy in Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma, 1-16.(IF 4.962)
Li, H., Lin, W., Zhang, G., Liu, R., Qu, M., Zhang, J., & **ng, X. (2023). BMSC-exosomes miR-25-3p Regulates the p53 Signaling Pathway Through PTEN to Inhibit Cell Apoptosis and Ameliorate Liver Ischemia‒reperfusion Injury. Stem Cell Reviews and Reports, 1-17.(IF 4.8)
Ha, N., Sun, J., Bian, Q., Wu, D., & Wang, X. (2022). Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development. Frontiers in Physiology, 13, 819619-819619.(IF 4.755)
Li, W., Ke, C., Yang, C., Li, J., Chen, Q., Xia, Z., & Xu, J. (2023). LncRNA DICER1‐AS1 promotes colorectal cancer progression by activating the MAPK/ERK signaling pathway through sponging miR‐650. Cancer Medicine.(IF 4.711)
Zhao, S., Liu, Q., Gao, F., & Hou, G. (2023). Development and Evaluation of a Novel Radiotracer 125 I-rIL-27 to Monitor Allotransplant Rejection by Specifically Targeting IL-27Rα. Molecular Imaging, 2023.(IF 4.488)
Zhu, M., Zhang, J., Yang, M., Zhang, H., Xu, T., Kan, F., ... & Yu, F. (2023). In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody. Journal of Cancer Research and Clinical Oncology, 1-14.(4.322)
Zhu, M., Zhang, J., Yang, M., Zhang, H., Xu, T., Kan, F., ... & Yu, F. (2023). In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody. Journal of Cancer Research and Clinical Oncology, 1-14.(4.322)(IF 4.322)
Cui, L., Shi, L., Li, D., Li, X., Su, X., Chen, L., ... & Chen, C. (2020). Real-ambient particulate matter exposure-induced cardiotoxicity in C57/B6 mice. Frontiers in Pharmacology, 11, 199.(IF 4.225)
Ren, H., Xia, X., Dai, X., & Dai, Y. (2022). The role of neuroplastin65 in macrophage against E. coli infection in mice. Molecular Immunology, 150, 78-89.(IF 4.174)
Song, T., Hu, Z., Zeng, C., Luo, H., & Liu, J. (2023). FLOT1, stabilized by WTAP/IGF2BP2 mediated N6-methyladenosine modification, predicts poor prognosis and promotes growth and invasion in gliomas. Heliyon, 9(6).(IF 3.776)
Zhang, L., Gao, J., Gong, A., Dong, Y., Hao, X., Wang, X., ... & Xu, W. (2022). The long noncoding RNA LINC00963 inhibits corneal fibrosis scar formation by targeting miR-143-3p. DNA and Cell Biology, 41(4), 400-409.(IF 3.55)
Li, F., Zhu, Z., Xue, M., He, W., Zhang, T., Feng, L., & Lin, S. (2019). siRNA-based breast cancer therapy by suppressing 17β-hydroxysteroid dehydrogenase type 1 in an optimized xenograft cell and molecular biology model in vivo.Drug design development and therapy, 13, 757.(IF 3.208)
You, W., Xu, Z., Di, A., Liu, P., Pang, C., Wang, J., ... & Zhao, G. (2021). Mechanism by Which Tong Xie Yao Fang Heals the Intestinal Mucosa of Rats with Ulcerative Colitis through the Hippo Pathway. Evidence-based Complementary and Alternative Medicine: Ecam, 2021, 5533914-5533914.(IF 2.65)
Luo, J., Zhao, P. Q., Chen, H. J., Liu, M. M., He, J. Q., & Fei, P. (2022). Procollagen C-proteinase enhancer 1 promotes physiologic retinal angiogenesis via regulating the process of collagen. International Journal of Ophthalmology, 15(6), 868.(IF 1.645)
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